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ECM is a key component of the tumor microenvironment that plays a central role in tumor cell proliferation and metastasis. Tissue-specific ECM substrates, including bone, liver, and lung ECMs, offer a robust, physiologically-relevant platform to study migration, invasion, or metastasis, or test compounds or immunotherapies.

Related Resources

White Paper: 3D Lung Tumor Model with Lung Extracellular Matrix to Predict Drug Efficacy
Application Note: IN SITE™ Metastasis Kit to Accelerate Anticancer Drug Development
Publication: Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers (2020)
Poster: TissueSpec® Bone, Liver, and Lung ECM Substrates Enable Disease-Relevant in-vitro Models of Pre-Metastatic Tissue Microenvironments
Webinar: Redefining Cancer Research with IN SITE™ Metastasis Kit